Quantifying Reductions in Plasmodium falciparum Infectivity to Mosquitos: A Sample Size Calculator to Inform Clinical Trials on Transmission-Reducing Interventions

Malaria transmission depends on the presence of mature Plasmodium transmission stages (gametocytes) that may render blood-feeding Anopheles mosquitos infectious. Transmission-blocking antimalarial drugs and vaccines can prevent transmission by reducing gametocyte densities or infectivity to mosquito...

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Detalhes bibliográficos

Principais autores:	Jordache Ramjith, Manon Alkema, John Bradley, Alassane Dicko, Chris Drakeley, Will Stone, Teun Bousema
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-06-01
Colecção:	Frontiers in Immunology
Assuntos:	malaria transmission gametocyte anopheles mosquito elimination
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.899615/full
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