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Context-Specific Metabolic Model Extraction Based on Regularized Least Squares Optimization.

Genome-scale metabolic models have proven highly valuable in investigating cell physiology. Recent advances include the development of methods to extract context-specific models capable of describing metabolism under more specific scenarios (e.g., cell types). Yet, none of the existing computational...

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Autors principals: Semidán Robaina Estévez, Zoran Nikoloski
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4497637?pdf=render
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