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Spinal overexpression of CAPN1 in CaMKII neurons mediates paclitaxel-induced neuropathic pain via NCS-1-TRPV4 signaling

Background: Paclitaxel (PTX), a widely administered chemotherapeutic drug, is known to cause neuropathic pain as a severe adverse effect. Elevated calpain expression in tumor tissues not only mediates chemoresistance but may also participate in the paclitaxel-induced neuropathic pain (PINP). There i...

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Principais autores: Ya-Ning Zhang, Shao-Xia Chen, Qiao-Yun Li, Jia-Qi You, Yao-Hui Zhou, Ying Zang
פורמט: Artigo
שפה:Inglês
יצא לאור: SAGE Publishing 2026-01-01
סדרה:Molecular Pain
גישה מקוונת:https://doi.org/10.1177/17448069251413873
תגים: הוספת תג
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