Reducing PDK1/Akt Activity: An Effective Therapeutic Target in the Treatment of Alzheimer’s Disease

Alzheimer’s disease (AD) is a common age-related neurodegenerative disease that leads to memory loss and cognitive function damage due to intracerebral neurofibrillary tangles (NFTs) and amyloid-β (Aβ) protein deposition. The phosphoinositide-dependent protein kinase (PDK1)/protein kinase B (Akt) si...

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Principais autores:	Shaobin Yang, Yaqin Du, Xiaoqian Zhao, Chendong Wu, Peng Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-05-01
coleção:	Cells
Assuntos:	Alzheimer’s disease amyloid-β Tau 3-phosphoinositide dependent kinase 1 protein kinase B phosphoinositide 3-kinase
Acesso em linha:	https://www.mdpi.com/2073-4409/11/11/1735
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