Albumin kinetics, intravascular fluid volume, and respiratory function in pigs ventilated at different levels of mechanical power following crystalloid vs. albumin infusion

Abstract Background The rationale of albumin use lies in its potential to increase oncotic pressure and optimize tissue perfusion. Randomized trials have not demonstrated a survival benefit, and the effects of albumin on volemia remain unclear. This study investigates, in healthy pigs, the effects o...

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Detalhes bibliográficos

Principais autores:	Simone Gattarello, Gaetano Gazzé, Emanuele Rollo, Beatrice Donati, Martina Caronna, Ilaria Grava, Carlo Chiumiento, Zhe Li, Walter Gallese, Domenico Nocera, Stefano Giovanazzi, Aurelio Sonzogni, Chiara Sonzogni, Alessandro Gatta, Francesca Collino, Luigi Camporota, Michael Quintel, Onnen Moerer, Federica Romitti, Luciano Gattinoni, Mattia Busana
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2026-02-01
coleção:	Intensive Care Medicine Experimental
Assuntos:	Fluid balance Mechanical power Mechanical ventilation Albumin Colloid Crystalloid
Acesso em linha:	https://doi.org/10.1186/s40635-026-00853-0
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