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Influence of Dystrophin Isoform Deficiency on Motor Development in Duchenne Muscular Dystrophy

ABSTRACT Objective In Duchenne muscular dystrophy (DMD), lack of the shorter dystrophin isoforms Dp140 and Dp71 is associated with increased central nervous system (CNS) involvement. We aimed to investigate how CNS involvement affects motor development in young DMD boys. Method Three hundred and for...

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Autors principals: Mary Chesshyre, Deborah Ridout, Georgia Stimpson, Laurent Servais, Giovanni Baranello, Adnan Manzur, UK NorthStar Clinical Network, Francesco Muntoni
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2025-09-01
Col·lecció:Annals of Clinical and Translational Neurology
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Accés en línia:https://doi.org/10.1002/acn3.70097
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