Cellular sentinels: empowering survival and immune defense in hematopoietic stem cell transplantation through mesenchymal stem cells and T lymphocytes

Abstract Background Hematopoietic stem cell transplantation (HSCT) is a critical treatment for hematologic disorders such as leukemia, lymphoma, and specific immune deficiencies. Despite its efficacy, challenges such as engraftment failure and delayed neutrophil regeneration remain significant barri...

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Principais autores:	Tzong-Shyuan Tai, Yun-Hsiang Chen, Chao-Ling Yao, Jiun-Han Lin, Yu-Shao Yang, Jai-Wen Shi, Li-Wen Fang, Duen-Wei Hsu, Shu-Chen Kuo, Shu-Ching Hsu
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-03-01
Series:	BMC Medicine
Assuntos:	Hematopoietic stem cell transplantation (HSCT) Engraftment enhancement Mesenchymal stem cells (MSCs) Activated T cells Neutrophil regeneration
Acceso en liña:	https://doi.org/10.1186/s12916-025-03987-2
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