The Heme Oxygenase/Biliverdin Reductase System and Its Genetic Variants in Physiology and Diseases
Heme oxygenase (HO) metabolizes heme into ferrous iron, carbon monoxide (CO), and biliverdin-IXα (BV), the latter being reduced into bilirubin-IXα (BR) by the biliverdin reductase-A (BVR). Heme oxygenase exists as two isoforms, HO-1, inducible and involved in the cell stress response, and HO-2, cons...
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| Formaat: | Artigo |
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MDPI AG
2025-02-01
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| Reeks: | Antioxidants |
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| Online toegang: | https://www.mdpi.com/2076-3921/14/2/187 |
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