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The role of SPRED1 mutation in melanoma

Abstract Melanoma is a highly malignant tumor, with its initiation and progression tightly linked to the aberrant activation of the MAPK signaling pathway. As a critical negative regulator of the MAPK pathway, SPRED1 frequently exhibits genomic alteration in melanoma, including gene deletions and mu...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Hui Hou, Jiao Li, Jianxiao Xing, Ruixia Hou
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2025-10-01
Rangatū:European Journal of Medical Research
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s40001-025-03267-y
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