Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA.
MicroRNAs (miRNAs) regulate gene expression posttranscriptionally by interfering with a target mRNA's translation, stability, or both. We sought to dissect the respective contributions of translational inhibition and mRNA decay to microRNA regulation. We identified direct targets of a specific miRNA...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2009-11-01
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| Colecção: | PLoS Biology |
| Acesso em linha: | http://europepmc.org/articles/PMC2766070?pdf=render |
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