Novel linkage and association of the mineralocorticoid receptor gene (NR3C2) with familial type 2 diabetes and depression and their comorbidity

Introduction: The mineralocorticoid receptor gene (NR3C2) appears to modulate stress and cognitive performance in patients with major depressive disorder (MDD). In addition, abnormalities in NR3C2 are associated in rodents with type 2 diabetes (T2D) and in humans with features of metabolic syndrome....

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Principais autores:	Mutaz Amin, Shumail Syed, Rongling Wu, Teodor T. Postolache, Claudia Gragnoli
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2023-01-01
Series:	Aspects of Molecular Medicine
Assuntos:	Nuclear receptor subfamily 3 group C member 2 NR3C2 Major depressive disorder MDD Type 2 diabetes Mineralcorticoid receptor antagonist
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2949688823000035
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