Unravelling the Shared Genetic Mechanisms Underlying 18 Autoimmune Diseases Using a Systems Approach

Autoimmune diseases (AiDs) are complex heterogeneous diseases characterized by hyperactive immune responses against self. Genome-wide association studies have identified thousands of single nucleotide polymorphisms (SNPs) associated with several AiDs. While these studies have identified a handful of...

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Detalhes bibliográficos

Principais autores:	Sreemol Gokuladhas, William Schierding, Evgeniia Golovina, Tayaza Fadason, Justin O’Sullivan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-08-01
coleção:	Frontiers in Immunology
Assuntos:	multiple autoimmune diseases shared gene regulatory mechanisms non-HLA module HLA module immune pathways cancer pathways
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.693142/full
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