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Exceptional responses to Trastuzumab deruxtecan in HER2-positive breast cancer: two illustrative case reports

BackgroundTrastuzumab deruxtecan (T-DXd), an antibody-drug conjugate targeting human epidermal growth factor receptor 2 (HER2), has demonstrated substantial clinical activity in metastatic HER2-positive breast cancer. Although durable responses are increasingly reported, the potential for long-lasti...

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Principais autores: Zelmira Ballatore, Helene Vanacker, Rita Chiari, Thomas Bachelot
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2025-10-01
Series:Frontiers in Oncology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fonc.2025.1647018/full
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