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Targeting Siderophore-Mediated Iron Uptake in <i>M. abscessus</i>: A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria

Targeting pathogenic mechanisms, rather than essential processes, represents a very attractive approach for the development of new antimycobacterial drugs. In this context, iron acquisition routes have recently emerged as potentially druggable pathways. However, the importance of siderophore biosynt...

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Asıl Yazarlar: Matteo Mori, Giovanni Stelitano, Giulia Cazzaniga, Arianna Gelain, Andrea Tresoldi, Mario Cocorullo, Martina Roversi, Laurent R. Chiarelli, Martina Tomaiuolo, Pietro Delre, Giuseppe F. Mangiatordi, Anna Griego, Loris Rizzello, Alberto Cassetta, Sonia Covaceuszach, Stefania Villa, Fiorella Meneghetti
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2023-02-01
Seri Bilgileri:Pharmaceutics
Konular:
antimicrobial resistance
cystic fibrosis
drug design
grating-coupled interferometry (GCI)
homology model
siderophores
Online Erişim:https://www.mdpi.com/1999-4923/15/2/502
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