Membrane-bound catechol-O-methyl transferase in cortical neurons and glial cells is intracellularly oriented

Catechol-O-methyl transferase (COMT) is involved in the inactivation of dopamine in brain regions in which the dopamine transporter (DAT1) is sparsely expressed. The membrane-bound isoform of COMT (MB-COMT) is the predominantly expressed form in the mammalian central nervous system (CNS). It has bee...

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Bibliographic Details

Main Authors:	Björn H Schott, Renato Frischknecht, Grazyna eDebska-Vielhaber, Nora John, Gusalija Behnisch, Emrah eDüzel, Eckart D Gundelfinger, Constanze I Seidenbecher
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2010-10-01
Series:	Frontiers in Psychiatry
Subjects:	Dopamine membrane neuronal cell culture catechol-O-methyl transferase immnunocytochemistry
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fpsyt.2010.00142/full
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