A Self-assembly Carrier-Free Nanovaccine based on Fluorinated CpG and Neoantigen Peptides for Hepatocellular Carcinoma Immunotherapy

Neoantigen peptides evade central thymic tolerance due to their absence in normal tissues, making neoantigen vaccines a leading strategy for personalized cancer immunotherapy. Although nanoparticle-based delivery systems are widely used to enhance neoantigen immunogenicity, traditional nanovaccines...

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Autori principali:	Xiuyun Lin, Hui Li, Jie Liu, Guangfeng Wu, Liuqing Yao, Zhouwei Zhan, Xiufang Yang, Xiu Yang, Shuxian Cai, Na Yao, Fengfang Chen, Wenqiang Yan, Peng Lyu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2026-12-01
Serie:	International Journal of Pharmaceutics: X
Soggetti:	Hepatocellular carcinoma Neoantigen nanovaccine Carrier-free nanovaccine；immunotherapy
Accesso online:	http://www.sciencedirect.com/science/article/pii/S259015672600126X
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