Genetic Mouse Models to Study Pancreatic Cancer-Induced Pain and Reduction in Well-Being

In addition to the poor prognosis, excruciating abdominal pain is a major challenge in pancreatic cancer. Neurotropism appears to be the underlying mechanism leading to neuronal invasion. However, there is a lack of animal models suitable for translationally bridging in vitro findings with clinical...

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Autores principales:	Michael Hirth, Yong Xie, Christiane Höper, Amandine Prats, Thilo Hackert, Matthias P. Ebert, Rohini Kuner
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2022-08-01
Colección:	Cells
Materias:	pancreatic ductal adenocarcinoma pain nerve hypertrophy KPC KPPC cytokines
Acceso en línea:	https://www.mdpi.com/2073-4409/11/17/2634
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