Structural studies on ribosomes of differentially macrolide-resistant Staphylococcus aureus strains
Macrolide resistance in Staphylococcus aureus is mediated by Erm-family methyltransferases, altering ribosomal drug binding. Using cryo-EM, we analyze solithromycin-bound ribosomes from resistant strains, revealing interactions that may enhance antibiotic efficacy. Antimicrobial resistance is a majo...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Life Science Alliance LLC
2025-08-01
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| Schriftenreihe: | Life Science Alliance |
| Online-Zugang: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503325 |
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