Fragile X mental retardation protein expression in Alzheimer’s disease
The FMR1 protein product, FMRP, is an mRNA binding protein associated with translational inhibition of target transcripts. One FMRP target is the amyloid precursor protein (APP) mRNA, and APP levels are elevated in Fmr1 KO mice. Given that elevated APP protein expression can elicit Alzheimer’s dis...
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| Автори: | , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2014-10-01
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| Серія: | Frontiers in Genetics |
| Предмети: | |
| Онлайн доступ: | http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00360/full |
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