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UBTF facilitates melanoma progression via modulating MEK1/2-ERK1/2 signalling pathways by promoting GIT1 transcription

Abstract Background UBTF is an HMGB-box DNA binding protein and a necessary Pol I/Pol II basal transcription factor. It has been found that UBTF involves in carcinogenesis and progression of a few cancers. Nevertheless, the the biological function and potential molecular mechanism of UBTF in melanom...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Jian Zhang, Jiaojiao Zhang, Wenli Liu, Rui Ge, Tianyuan Gao, Qiong Tian, Xin Mu, Lingyu Zhao, Xu Li
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2021-10-01
Rangatū:Cancer Cell International
Ngā marau:
UBTF
GIT1
Melanoma
Proliferation
MEK1/2-ERK1/2 signalling pathways
Urunga tuihono:https://doi.org/10.1186/s12935-021-02237-8
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