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Central role of the Holliday junction helicase RuvAB in vlsE recombination and infectivity of Borrelia burgdorferi.

Antigenic variation plays a vital role in the pathogenesis of many infectious bacteria and protozoa including Borrelia burgdorferi, the causative agent of Lyme disease. VlsE, a 35 kDa surface-exposed lipoprotein, undergoes antigenic variation during B. burgdorferi infection of mammalian hosts, and i...

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Bibliografiske detaljer
Principais autores: Tao Lin, Lihui Gao, Diane G Edmondson, Mary B Jacobs, Mario T Philipp, Steven J Norris
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2009-12-01
Serier:PLoS Pathogens
Online adgang:http://europepmc.org/articles/PMC2780311?pdf=render
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