EWSR1 prevents the induction of aneuploidy through direct regulation of Aurora B
EWSR1 (Ewing sarcoma breakpoint region 1) was originally identified as a part of an aberrant EWSR1/FLI1 fusion gene in Ewing sarcoma, the second most common pediatric bone cancer. Due to formation of the EWSR1/FLI1 fusion gene in the tumor genome, the cell loses one wild type EWSR1 allele. Our previ...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2023-02-01
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| Serie: | Frontiers in Cell and Developmental Biology |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fcell.2023.987153/full |
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