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JunB Is Critical for Survival of T Helper Cells

Clonal expansion and differentiation of various T helper subsets, such as Th1, Th2, and Th17 cells, depend on a complex of transcription factors, IRF4 and a BATF-containing AP-1 heterodimer. A major BATF heterodimeric partner, JunB, regulates Th17 differentiation, but the role of JunB in other T hel...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Tsunghan Hsieh, Daiki Sasaki, Naoyuki Taira, Hsiaochiao Chien, Shukla Sarkar, Yu Seto, Mio Miyagi, Hiroki Ishikawa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2022-06-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2022.901030/full
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