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Challenges and opportunities associated with the MD Anderson IMPACT2 randomized study in precision oncology

Abstract We investigated the challenges of conducting IMPACT2, an ongoing randomized study that evaluates molecular testing and targeted therapy (ClinicalTrials.gov: NCT02152254). Patients with metastatic cancer underwent tumor profiling and were randomized between the two arms when eligibility crit...

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Bibliographic Details
Main Authors: Henry Hiep Vo, Siqing Fu, David S. Hong, Daniel D. Karp, Sarina Piha-Paul, Vivek Subbiah, Filip Janku, Aung Naing, Timothy A. Yap, Jordi Rodon, Jaffer A. Ajani, Carrie Cartwright, Amber Johnson, I-Wen Song, Jennifer Beck, Michael Kahle, Graciela M. Nogueras-Gonzalez, Vincent Miller, Calvin Chao, David J. Vining, Donald A. Berry, Funda Meric-Bernstam, Apostolia-Maria Tsimberidou
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2022-10-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00317-0
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