Delphinidin prevents high glucose-induced cell proliferation and collagen synthesis by inhibition of NOX-1 and mitochondrial superoxide in mesangial cells

This study examined the effect of delphinidin on high glucose-induced cell proliferation and collagen synthesis in mesangial cells. Glucose dose-dependently (5.6–25 mM) increased cell proliferation and collagen I and IV mRNA levels, whereas pretreatment with delphinidin (50 μM) prevented cell prolif...

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Autors principals:	Seung Eun Song, Hye Jun Jo, Yong-Woon Kim, Young-Je Cho, Jae-Ryong Kim, So-Young Park
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2016-04-01
Col·lecció:	Journal of Pharmacological Sciences
Matèries:	Delphinidin High glucose Mesangial cells NOX-1 Reactive oxygen species
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S1347861316000402
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