Treatment With an Angiopoietin-1 Mimetic Peptide Improves Cognitive Outcome in Rats With Vascular Dementia

Background and PurposeVascular dementia (VaD) is a complex neurodegenerative disease affecting cognition and memory. There is a lack of approved pharmacological treatments specifically for VaD. In this study, we investigate the therapeutic effects of AV-001, a Tie2 receptor agonist, in middle-aged r...

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Detalhes bibliográficos

Principais autores:	Lauren Culmone, Brianna Powell, Julie Landschoot-Ward, Alex Zacharek, Huanjia Gao, Elizabeth L. Findeis, Ayesha Malik, Mei Lu, Michael Chopp, Poornima Venkat
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-05-01
coleção:	Frontiers in Cellular Neuroscience
Assuntos:	angiopoietin-1 cognition microinfarct dementia vasculotide vascular dementia (VaD) white matter remodeling
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fncel.2022.869710/full
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