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Azelnidipine Exhibits In Vitro and In Vivo Antiviral Effects against Flavivirus Infections by Targeting the Viral RdRp

Flaviviruses, represented by Zika and dengue virus (ZIKV and DENV), are widely present around the world and cause various diseases with serious consequences. However, no antiviral drugs have been clinically approved for use against them. Azelnidipine (ALP) is a dihydropyridine calcium channel blocke...

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Principais autores: Zhuang Wang, Yunzheng Yan, Qingsong Dai, Yijie Xu, Jiye Yin, Wei Li, Yuexiang Li, Xiaotong Yang, Xiaojia Guo, Miaomiao Liu, Xingjuan Chen, Ruiyuan Cao, Wu Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-06-01
coleção:Viruses
Assuntos:
azelnidipine
Zika virus
antiviral
flavivirus
RdRp
Acesso em linha:https://www.mdpi.com/1999-4915/14/6/1228
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