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MICAL1 activation by PAK1 mediates actin filament disassembly

Summary: The MICAL1 monooxygenase is an important regulator of filamentous actin (F-actin) structures. Although MICAL1 has been shown to be regulated via protein-protein interactions at the autoinhibitory carboxyl terminus, a link between actin-regulatory RHO GTPase signaling pathways and MICAL1 has...

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Bibliografiske detaljer
Principais autores: David J. McGarry, Giovanni Castino, Sergio Lilla, Alexandre Carnet, Loughlin Kelly, Katarina Micovic, Sara Zanivan, Michael F. Olson
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-10-01
Serier:Cell Reports
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2211124722012839
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