Weak HIF-1alpha expression indicates poor prognosis in resectable pancreatic ductal adenocarcinoma

Abstract Background HIF-1alpha and CAIX proteins are commonly expressed under hypoxic conditions, but other regulatory factors have been described as well. Pancreatic ductal adenocarcinoma (PDAC) is characterized by hypoxia and strong stromal reaction and has a dismal prognosis with the currently av...

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Autores principales:	Joni Leppänen, Olli Helminen, Heikki Huhta, Joonas H. Kauppila, Joel Isohookana, Kirsi-Maria Haapasaari, Seppo Parkkila, Juha Saarnio, Petri P. Lehenkari, Tuomo J. Karttunen
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2018-07-01
Colección:	World Journal of Surgical Oncology
Materias:	HIF-1alpha Carbonic anhydrase 9 Pancreatic ductal adenocarcinoma
Acceso en línea:	http://link.springer.com/article/10.1186/s12957-018-1432-4
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