Complete spatially resolved gene expression is not necessary for identifying spatial domains

Summary: Spatially resolved transcriptomics (SRT) technologies have revolutionized the study of tissue organization. We introduce a graph convolutional network with an attention and positive emphasis mechanism, termed BINARY, relying exclusively on binarized SRT data to accurately delineate spatial...

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Detalhes bibliográficos

Principais autores:	Senlin Lin, Yan Cui, Fangyuan Zhao, Zhidong Yang, Jiangning Song, Jianhua Yao, Yu Zhao, Bin-Zhi Qian, Yi Zhao, Zhiyuan Yuan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-06-01
coleção:	Cell Genomics
Assuntos:	spatial omics spatially resolved transcriptomics spatially resolved gene expression spatial domain spatial clustering bioinformatics
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2666979X24001319
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