Novel hybrid motifs of 4-nitroimidazole-piperazinyl tagged 1,2,3-triazoles: Synthesis, crystal structure, anticancer evaluations, and molecular docking study

4-((4-(1-benzyl-2-methyl-4-nitro-1H-imidazole-5-yl)piperazine-1-yl)methyl)-1-substituted-1H-1,2,3-triazole motifs are designed and synthesized via click chemistry. The reaction of 1-(N1-benzyl- 2-methyl-4-nitro-1H-imidazole- 5-yl)-4-(prop-2-yn-1-yl) piperazine 5 as new scaffold with diverse primary...

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Autors principals:	SadeekahO.W. Saber, Raed A. Al-Qawasmeh, Luay Abu-Qatouseh, Amneh Shtaiwi, Monther A. Khanfar, Yaseen A. Al-Soud
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2023-09-01
Col·lecció:	Heliyon
Matèries:	Synthesis Click chemistry 4-Nitroimidazole-tagged 1,2,3-triazoles Anticancer Molecular docking study
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2405844023065350
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