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Targeting hyaluronan synthesis enhances the therapeutic effectiveness of biologics in inflammatory bowel disease

Although biologics have been revolutionizing the treatment of inflammatory bowel diseases (IBD) over the past decade, a significant number of patients still fail to benefit from these drugs. Overcoming the nonresponse to biologics is one of the top challenges in IBD treatment. In this study, we reve...

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Detalhes bibliográficos
Principais autores: Peng Xiao, Zhehang Chen, Xuechun Cai, Wenhao Xia, Xia Liu, Zhangfa Song, Huijuan Wang, Yuening Zhao, Youling Huang, Yu Zhang, Ke Guo, Haotian Chen, Rongbei Liu, Changcheng Meng, Yanfei Fang, Yunkun Lu, Qian Cao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical investigation 2025-01-01
coleção:JCI Insight
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Acesso em linha:https://doi.org/10.1172/jci.insight.180425
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