QR Code

Desialylation of <i>O</i>-glycans on glycoprotein Ibα drives receptor signaling and platelet clearance

During infection neuraminidase desialylates platelets and induces their rapid clearance from circulation. The underlying molecular basis, particularly the role of platelet glycoprotein (GP)Ibα therein, is not clear. Utilizing genetically altered mice we report that the extracellular domain of GPIbα...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yingchun Wang, Wenchun Chen, Wei Zhang, Melissa M. Lee-Sundlov, Caterina Casari, Michael C. Berndt, Francois Lanza, Wolfgang Bergmeier, Karin M. Hoffmeister, X. Frank Zhang, Renhao Li
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Ferrata Storti Foundation 2020-01-01
Rangatū:Haematologica
Urunga tuihono:https://haematologica.org/article/view/9627
Ngā Tūtohu: Tāpirihia he Tūtohu
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!