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Muscimol inhibits plasma membrane rupture and ninjurin-1(NINJ1) oligomerization during pyroptosis

Abstract Pyroptosis is a cell death process that causes inflammation and contributes to numerous diseases. Pyroptosis is mediated by caspase-1 family proteases that cleave the pore-forming protein gasdermin D, causing plasma membrane rupture and release of pathogenic cellular contents. We previously...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Andreas B. den Hartigh, Wendy P. Loomis, Marisa J. Anderson, Bente Frølund, Susan L. Fink
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Portfolio 2023-10-01
Цуврал:Communications Biology
Онлайн хандалт:https://doi.org/10.1038/s42003-023-05354-4
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