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Role of cytarabine in paediatric acute promyelocytic leukemia treated with the combination of all-trans retinoic acid and arsenic trioxide: a randomized controlled trial

Abstract Background The combination of all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO) has been suggested to be safe and effective for adult acute promyelocytic leukaemia (APL). As of 2010, the role of cytarabine (Ara-C) in APL was controversial. The aim of this study was to test the effic...

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Principais autores: Li Zhang, Yao Zou, Yumei Chen, Ye Guo, Wenyu Yang, Xiaojuan Chen, Shuchun Wang, Xiaoming Liu, Min Ruan, Jiayuan Zhang, Tianfeng Liu, Fang Liu, Benquan Qi, Wenbin An, Yuanyuan Ren, Lixian Chang, Xiaofan Zhu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-04-01
Serier:BMC Cancer
Fag:
Acute promyelocytic leukaemia
All-trans retinoic acid
Arsenic trioxide
Paediatric
Cytarabine
Online adgang:http://link.springer.com/article/10.1186/s12885-018-4280-2
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