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Trabectedin and Plitidepsin: Drugs from the Sea that Strike the Tumor Microenvironment

The prevailing paradigm states that cancer cells acquire multiple genetic mutations in oncogenes or tumor suppressor genes whose respective activation/up-regulation or loss of function serve to impart aberrant properties, such as hyperproliferation or inhibition of cell death. However, a tumor is no...

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Auteurs principaux: Carlos M. Galmarini, Maurizio D'Incalci, Paola Allavena
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2014-01-01
Collection:Marine Drugs
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Accès en ligne:http://www.mdpi.com/1660-3397/12/2/719
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