Ophiocordyceps sinensis-induced changes in Thitarodes xiaojinensis: from intestinal barrier destruction, microbiome dysbiosis to immune responses at the molecular level

Abstract Background The entomopathogenic fungus (EPF) Ophiocordyceps sinensis has a long-term coexistence with its host insect, Thitarodes xiaojinensis, making it a unique model for host–pathogen interactions. Hemolymph, a critical component in insects, plays an essential role in maintaining both nu...

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Detalhes bibliográficos

Principais autores:	Xiu-wen Bao, Qing-he Wang, Ting Li, Yong Li, Zhi-ying Bian, Si-jing Liu, Li-ying He, Shu-qi Niu, Jin-lin Guo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-07-01
coleção:	BMC Biology
Assuntos:	Ophiocordyceps sinensis Thitarodes xiaojinensis Immune Hemolymph microbiome Antimicrobial peptide
Acesso em linha:	https://doi.org/10.1186/s12915-025-02277-w
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