A randomized trial of low-dose thrombolysis, ultrasound-assisted thrombolysis, or heparin for intermediate-high risk pulmonary embolism—the STRATIFY trial: design and statistical analysis plan

Abstract Background Intermediate-high risk pulmonary embolism (PE) carries a significant risk of hemodynamic deterioration or death. Treatment should balance efficacy in reducing clot burden with the risk of complications, particularly bleeding. Previous studies on high-dose, short-term thrombolysis...

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Autori principali:	Jesper Kjærgaard, Jørn Carlsen, Emilie Sonne-Holm, Sebastian Wiberg, Lene Holmvang, Jens Flensted Lassen, Rikke Sørensen, Dan Høfsten, Peter Sommer Ulriksen, Samir Jawad, Pernille Palm, Jens Jakob Thune, Christian Hassager, Ole P. Kristiansen, Kristian Eskesen, Søren Fanø, Lia E. Bang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-12-01
Serie:	Trials
Soggetti:	Pulmonary embolism Intermediate-high risk Low-dose thrombolysis Ultrasound-assisted thrombolysis Clot burden
Accesso online:	https://doi.org/10.1186/s13063-024-08688-4
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