Core 2 β1,6-N-acetylglucosaminyltransferases accelerate the escape of choriocarcinoma from natural killer cell immunity

Hyperglycosylated human chorionic gonadotropin (H-hCG) is secreted from choriocarcinoma and contains a core2 O-glycan formed by core2 β1,6-N-acetylglucosaminyl transferase (C2GnT). Choriocarcinoma is considered immunogenic as it is gestational and contains paternal chromosomal components. Here we ex...

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Detalhes bibliográficos

Principais autores:	Kenichi Nakamura, Kaoru Niimi, Eiko Yamamoto, Yoshiki Ikeda, Kimihiro Nishino, Shiro Suzuki, Hiroaki Kajiyama, Fumitaka Kikkawa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-07-01
coleção:	Biochemistry and Biophysics Reports
Assuntos:	Choriocarcinoma C2GnT Natural killer cell O-glycan Immunosuppression
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405580821000455
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