AI-guided optimization and eco-friendly assessment of in lab stability-indicating HPLC method for empagliflozin and sitagliptin in combined pharmaceutical dosage form

An accurate analytical method is necessary for accurate quantification and stability assessment of novel antidiabetic fixed dose combination of empagliflozin and sitagliptin phosphate monohydrate. Artificial intelligence has shown promise in predicting chromatographic conditions, but experimental va...

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Autors principals:	Ashok H. Akabari, Ashim Kumar Sen, Yadav Ragini, Ketan V. Shah, Mohammad Khishe, Ghanshyam G. Tejani
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-08-01
Col·lecció:	Results in Chemistry
Matèries:	HPLC method development Empagliflozin and Sitagliptin estimation AI-guided chromatography Stability-indicating method Green analytical chemistry
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2211715626005552
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