Biochemical and biophysical characterization of four EphB kinase domains reveals contrasting thermodynamic, kinetic and inhibition profiles

The Eph (erythropoietin-producing hepatocellular carcinoma) B receptors are important in a variety of cellular processes through their roles in cell-to-cell contact and signalling; their up-regulation and down-regulation has been shown to have implications in a variety of cancers. A greater understa...

詳細記述

書誌詳細

主要な著者:	Ross C. Overman, Judit E. Debreczeni, Caroline M. Truman, Mark S. McAlister, Teresa K. Attwood
フォーマット:	Artigo
言語:	Inglês
出版事項:	Portland Press 2013-06-01
シリーズ:	Bioscience Reports
主題:	EphB1 EphB2 EphB3 EphB4 kinase inhibition protein stability
オンライン･アクセス:	http://www.bioscirep.org/bsr/033/e040/bsr033e040.htm
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