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TERT promoter mutations contribute to adverse clinical outcomes and poor prognosis in radioiodine refractory differentiated thyroid cancer

Abstract Telomerase reverse transcriptase promoter (TERTp) mutations are associated with non-radioiodine avidity. However, the role of these mutations in the clinical outcomes of patients with radioiodine-refractory differentiated thyroid cancer (RAIR-DTC) remains unknown. Herein, we aim to analyze...

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Principais autores: Gongxun Tan, Bingquan Jin, Xiaoqin Qian, Yuguo Wang, Guoliang Zhang, Enock Adjei Agyekum, Feng Wang, Liang Shi, Yue Zhang, Zhenwei Mao, Chunhe Shi, Ying Xu, Xiuying Li, Lele Zhang, Shaohua Li
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-10-01
Serier:Scientific Reports
Fag:
TERT promoter mutations
Differentiated thyroid cancer
Multifocal metastases
Iodine refractory differentiated thyroid cancer
Radioiodine therapy
Nuclear medicine
Online adgang:https://doi.org/10.1038/s41598-024-75087-9
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