Primordial germ cell-like cells residing in the pituitary may serve as the origin of intracranial germ cell tumors

Abstract Intracranial germ cell tumors (iGCTs) are rare, histologically classified as extragonadal germ cell tumors, and predominantly affect children and adolescents. These tumors are commonly found in the midline of the brain, with a notable male predominance and varying geographic incidences. The...

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Hlavní autoři:	Yi Zhang, Lei Zhang, Zhengyang Shen, Jifang Liu, Zhang Ye, Kan Deng, Yong Yao, Daishu Han
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-02-01
Edice:	Scientific Reports
Témata:	Intracranial germ cell tumors Primordial germ cell-like cells Pituitary gland Germ cell markers Tumorigenesis
On-line přístup:	https://doi.org/10.1038/s41598-026-38060-2
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