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Structural basis of actin monomer re-charging by cyclase-associated protein

Depolymerized ADP-actin monomers must be recharged with ATP for new rounds of filament assembly. Here the authors show that cyclase-associated protein (CAP) catalyzes actin nucleotide exchange in vivo and their CAP–actin complex structure reveals the molecular mechanism of CAP-mediated actin nucleot...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Tommi Kotila, Konstantin Kogan, Giray Enkavi, Siyang Guo, Ilpo Vattulainen, Bruce L. Goode, Pekka Lappalainen
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2018-05-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-018-04231-7
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