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Ionizable polymeric nanocarriers for the codelivery of bi-adjuvant and neoantigens in combination tumor immunotherapy

Ionizable lipid nanocarriers have made historical contribution to COVID-19 mRNA vaccines. Here, we report ionizable polymeric nanoparticles that co-deliver bi-adjuvant and neoantigen peptides for cancer immunotherapy in combination with immune checkpoint blockade (ICB). Current cancer ICB benefits o...

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Principais autores: Ting Su, Xiang Liu, Shuibin Lin, Furong Cheng, Guizhi Zhu
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Communications Co., Ltd. 2023-08-01
Serier:Bioactive Materials
Fag:
Polymeric nanoparticles
Combination adjuvants
Cancer neoantigen
Nanovaccine codelivery
Cancer immunotherapy
Online adgang:http://www.sciencedirect.com/science/article/pii/S2452199X23000567
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