Coupling antitoxins and blue/white screening with parAB/resolvase mutation as a strategy for Salmonella spp. plasmid curing

ABSTRACT Despite the dissemination of multidrug resistance plasmids, including those carrying virulence genes in Salmonella spp., efficient plasmid curing tools are lacking. Plasmid partitioning and multimer resolution systems are attractive targets for plasmid cure. However, plasmid curing strategi...

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Autori principali:	Dereje D. Gudeta, Shaohua Zhao, Nesreen Aljahdali, Steven L. Foley
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2024-11-01
Serie:	Microbiology Spectrum
Soggetti:	plasmid curing parA mutation toxin/antitoxin systems blue white screening plasmid stability
Accesso online:	https://journals.asm.org/doi/10.1128/spectrum.01220-24
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