In utero exposure to endogenous maternal polyclonal anti-Caspr2 antibody leads to behavioral abnormalities resembling autism spectrum disorder in male mice
Abstract The concept that exposure in utero to maternal anti-brain antibodies contributes to the development of autism spectrum disorders (ASD) has been entertained for over a decade. We determined that antibodies targeting Caspr2 are present at high frequency in mothers with brain-reactive serology...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Portfolio
2020-09-01
|
| Schriftenreihe: | Scientific Reports |
| Online-Zugang: | https://doi.org/10.1038/s41598-020-71201-9 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|