A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation
Cryo-EM structures reveal the role of glutathione (GSH) in poliovirus (PV) serotype 3 virus-like particle (VLP) stability, suggesting GSH or an analogous tight-binding antiviral offers potential for stabilizing VLP vaccines against PV.
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Portfolio
2022-11-01
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| Col·lecció: | Communications Biology |
| Accés en línia: | https://doi.org/10.1038/s42003-022-04252-5 |
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