Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value

Neurofilament-light chain (NF-L) is a well-known clinical biomarker of many neurodegenerative diseases. By analyzing amyotrophic lateral sclerosis (ALS) patients cerebrospinal fluid (CSF) or plasma, progression of NF-L levels can forecast conversion from the presymptomatic to symptomatic stage and t...

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Detalhes bibliográficos

Principais autores:	Tina Loeffler, Irene Schilcher, Stefanie Flunkert, Birgit Hutter-Paier
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-06-01
coleção:	Frontiers in Neuroscience
Assuntos:	Neurofilament-light chain biomarker neurodegenerative disease lysosomal storage diseases plasma cerebrospinal fluid
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fnins.2020.00579/full
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