Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo
Summary: Hematopoietic stem cells (HSCs) maintain lifelong hematopoiesis by remaining quiescent in the bone marrow niche. Recapitulation of a quiescent state in culture has not been achieved, as cells rapidly proliferate and differentiate in vitro. After exhaustive analysis of different environmenta...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2019-07-01
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| Schriftenreihe: | Cell Reports |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S2211124719307661 |
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